Efficacy of Boesenbergia rotunda Treatment against Thioacetamide-Induced Liver Cirrhosis in a Rat Model

Table 6

Effect of BR ethanol extract on serum lipid profiles at the end of the 8-week study.

Treatment	Cholesterol mmol/L	HDL; mmol/L	LDL; mmol/L	Triglycerides mmol/L
Group 1; (normal rats)	1.42±0.05	1.13±0.04	0.13±0.02	1.27±0.03
Group 2; (rats with cirrhosis)	3.22±0.06 **	0.53±0.04 **	2.50±0.10 **	2.83±0.07 **
Group 3; (Silymarin-treated rats)	1.80±0.04	1.32±0.04	0.33±0.03	1.45±0.04
Group 4; (treatment with the BR extract at 250 mg/kg dose)	2.00±0.06 *	0.62±0.07	1.22±0.07 *	1.78±0.03 *
Group 5; (treatment with the BR extract at 500 mg/kg dose)	1.57±0.05 *	1.17±0.05 *	0.23±0.02 *	1.42±0.05 *

Means between the silymarin-treated Group 3, low-dose BR-treated Group 4, and high-dose BR-treated Group 5 had significant differences when compared with the cirrhosis control Group 2 with *𝑃<0.001 and compared with the normal control Group 1 with **𝑃<0.001.