Animal Models as Tools to Investigate Antidiabetic and Anti-Inflammatory Plants

Table 3

The doses of two chemical diabetogenes in different species.

Chemicals	Species	Dose (s) in mg/kg
Alloxan	Rat	40–200 (i.v./i.p.)
	Mice	50–200 (i.v./i.p.)
	Rabbit	100–150 (i.v.)
	Dog	50–75 (i.v.)
Streptozotocin	Rat	35–65 (i.v./i.p.)
	Mice	100–200 (i.v./i.p.)
	Hamster	50 (i.p.)
	Dog	20–30 (i.v.)
	Pig	100–150 (i.v.)
	Primates	50–150 (i.v.)

i.v.: intravenous; i.p.: intraperitoneal.
After [40].