Isolation of Antidiabetic Principle from Fruit Rinds of Punica granatum
Figure 5
Effect of MEPG and VAD on alloxan-induced cellular damage of pancreas. (a) Normal control (normal cytoarchitecture of pancreas), (b) diabetic control (significant loss of islets and sever acinar damage), (c) glibenclamide (near normal structure of pancreas), (d) MEPG (200 mg/kg) (moderate acinar damage and very minimal number of pancreatic islets), (e) MEPG (400 mg/kg) (mild acinar damage and pancreatic islets), (f) VAD (10 mg/kg) (moderate acinar damage and minimal number of pancreatic islets), (g) VAD (25 mg/kg) (mild acinar damage and sufficient number of pancreatic islets), and (h) VAD (50 mg/kg) (very mild acinar damage and nearly normal pancreatic islets).
