Isolation of Antidiabetic Principle from Fruit Rinds of Punica granatum

Table 3

Effect of MEPG and VAD isolated from fruit rinds of Punica granatum on protein tyrosine phosphatase-1B (PTP1B) enzyme activity in in vitro.

Sl. no	Sample	Concentration (𝜇g/mL)	% Inhibition^#	IC50 (𝜇g/mL)^*
		5	21.6±0.24
		10	39.6±0.15
(1)	Methanolic extract	25	55.4±0.22	26.25
		50	78.7±0.34
		100	98.9±0.22
		5	33.3±0.35
		10	46.7±0.54
(2)	Valoneic acid dilactone	25	68.5±0.64	12.41
		50	84.0±0.11
		100	98.5±0.75

Values are expressed as mean ± SEM (% inhibition^#) and mean (IC^∗₅₀) of three trials.