Isolation of Antidiabetic Principle from Fruit Rinds of Punica granatum
Effect of repeated-dose oral administration of MEPG and VAD on oral glucose tolerance test (OGTT) in alloxan-induced diabetic rats on the 21st day.
Blood glucose (mg/dL)
Vehicle control (3% Tween 80) 10 mL/kg, p.o.
Glibenclamide-10 mg/kg, p.o.
MEPG-200 mg/kg, p.o.
MEPG-400 mg/kg, p.o.
VAD-10 mg/kg, p.o.
VAD-25 mg/kg, p.o.
VAD-50 mg/kg, p.o.
All the values are expressed as mean ± SEM, compared to normal control, and compared to vehicle control (3% Tween 80).
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