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Evidence-Based Complementary and Alternative Medicine
Volume 2012, Article ID 149256, 13 pages
Research Article

A Standardized Chinese Herbal Decoction, Kai-Xin-San, Restores Decreased Levels of Neurotransmitters and Neurotrophic Factors in the Brain of Chronic Stress-Induced Depressive Rats

1Division of Life Science, Center for Chinese Medicine and State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science and Technology, Clear Water Bay Road, Hong Kong
2School of Chinese Medicine, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong

Received 20 April 2012; Revised 16 June 2012; Accepted 10 July 2012

Academic Editor: Kelvin Chan

Copyright © 2012 Kevin Yue Zhu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Supplementary Figure (A): Fingerprint chromatogram of KXS was made by HPLC-DAD at wavelength of 330 nm. The identification of 3, 6’-disinapoyl sucrose (1), α-asarone (7) and β-asarone (6) were shown in the chromatogram.

Supplementary Figure (B): Fingerprint chromatogram of KXS was made by HPLC-MS/MS method at negative scan mode. The identification of ginsenoside Rg1 (2), Re (3), Rb1 (4), Rd (5), and pachymic acid (8) were shown in the chromatogram. Representative chromatograms are shown, n=3.

  1. Supplementary Figure