Table 2: Neuroprotective effects of 4-phenylcoumarins (200 μM) isolated from hexane bark of M. kunstleri against H2O2-induced apoptosis in NG108-15 cells.

CompoundaCell viability (%)b

Control100
1
2
3
4
5
EGCG (50 μM)d

The values shown are the means ± SE of at least three independent experiments.
aNG108-15 cells were pretreated with 4-phenylcoumarins (3.125–200 μM) for 2 h prior to exposure to H2O2 (2 mM). After incubation, cells were assessed by MTT to determine the percentage viability.
bCell viability was measured by MTT assay.
cH2O2-treated value differed significantly from the untreated control at the level of .
dEGCG was used as standard positive control.
#Results differ significantly from H2O2-treated group compared to the control untreated group: .
*Significantly from H2O2-treated group compared to the treatment group: .