Effect of Methanolic Leaf Extract of Ocimum basilicum L. on Benzene-Induced Hematotoxicity in Mice

Table 3

Evaluation of nontoxicity of the plant material. Effect of leaf methanolic extract on serum biochemical, hematological parameters, and body weight after subacute administration. Data are represented as mean ± SEM.

Parameters	Control	Lower dose (50 mg/Kg body weight)	Higher dose (1500 mg/Kg body weight)
	(group I)	(group II)	(group III)
SGOT (IU/dL)	40.75 ± 1.12	41.08 ± 1.19	40.96 ± 1.15
SGPT (IU/ dL)	34.22 ± 1.19	34.98 ± 1.16	35.11 ± 1.13
ALP (IU/dL)	81.12 ± 1.78	80.56 ± 1.76	80.01 ± 1.72
Bilirubin (mg/dL)	0.86 ± 0.13	0.85 ± 0.11	0.86 ± 0.12
Cholesterol (mg/dL)	149.25 ± 9.3	150.33 ± 8.7	150.69 ± 8.9
Total protein (mg/dL)	6.90 ± 2.09	6.89 ± 2.01	6.98 ± 2.33
Urea (mg/dL)	41.64 ± 1.32	42.09 ± 1.21	42.67 ± 1.31
Uric acid (mg/dL)	5.48 ± 1.77	5.12 ± 1.56	5.19 ± 1.67
Creatinine (mg/mL)	0.93 ± 0.12	0.91 ± 0.21	0.92 ± 0.18
RBC (× 10^12/L)	6.6 ± 0.12	6.6 ± 0.16	6.7 ± 0.13
Hb (g/dL)	13.2 ± 0.22	13.1 ± 0.28	12.9 ± 0.31
WBC (× 10^9/L)	31.3 ± 0.42	31.2 ± 0.0.38	32.1 ± 0.26
Platelet (× 10^9/L)	756 ± 41.2	736 ± 46.1	750 ± 42.4
Body weight (g)	23 ± 1.2	23 ± 1.5	23 ± 1.4