Activations of Both Extrinsic and Intrinsic Pathways in HCT 116 Human Colorectal Cancer Cells Contribute to Apoptosis through p53-Mediated ATM/Fas Signaling by Emilia sonchifolia Extract, a Folklore Medicinal Plant

Table 1

The IC₅₀ values for 24 hour-treatment of ESE in different p53 gene expression cell lines (mean ± S.D. of three independent experiments).

Cell line		p53 gene expression	IC50 (μg/mL)
HCT 116	Human colorectal cancer cell lines	Wild-type	50.54±2.28
SW480		Mutation (Arg^273→His)	79.62±6.05
HT29		Mutation (Arg^273→His)	88.54±4.01
A549	Human nonsmall cell lung cancer cell lines	Wild-type	53.69±3.17
H1299		Null	121.36±5.33