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Evidence-Based Complementary and Alternative Medicine
Volume 2012 (2012), Article ID 185167, 13 pages
http://dx.doi.org/10.1155/2012/185167
Research Article

The Inhibition of Spinal Astrocytic JAK2-STAT3 Pathway Activation Correlates with the Analgesic Effects of Triptolide in the Rat Neuropathic Pain Model

1Department of Anatomy, Histology and Embryology and K. K. Leung Brain Research Centre, The Fourth Military Medical University, Xi'an 710032, China
2Department of Anesthesiology, School of Stomatology, The Fourth Military Medical University, Xi'an 710032, China
3Department of Neurosurgery, Tangdu Hospital, The Fourth Military Medical University, Xi'an 710038, China

Received 19 August 2012; Accepted 16 November 2012

Academic Editor: Mei Tian

Copyright © 2012 Jun Tang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [16 citations]

The following is the list of published articles that have cited the current article.

  • Xiaodong Liu, Yuanyuan Tian, Na Lu, Tony Gin, Christopher H. K. Cheng, and Matthew T. V. Chan, “Stat3 Inhibition Attenuates Mechanical Allodynia through Transcriptional Regulation of Chemokine Expression in Spinal Astrocytes,” PLoS ONE, vol. 8, no. 10, 2013. View at Publisher · View at Google Scholar
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  • Jian-Ming Li, Yan Zhang, Liang Tang, Yong-Heng Chen, Qian Gao, Mei-Hua Bao, De-Liang Lei, and Ju Xiang, “Effects of triptolide on hippocampal microglial cells and astrocytes in the APP/PS1 double transgenic mouse model of Alzheimer’s disease,” Neural Regeneration Research, vol. 11, no. 9, pp. 1492–1498, 2016. View at Publisher · View at Google Scholar
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  • Xiaofan Hu, Yulin Dong, Xiaohang Jin, Chunkui Zhang, Ting Zhang, Jie Zhao, Juan Shi, and Jinlian Li, “The novel and potent anti-depressive action of triptolide and its influences on hippocampal neuroinflammation in a rat model of depression comorbidity of chronic pain,” Brain, Behavior, and Immunity, 2017. View at Publisher · View at Google Scholar
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