Chronic Administration of Oil Palm (Elaeis guineensis) Leaves Extract Attenuates Hyperglycaemic-Induced Oxidative Stress and Improves Renal Histopathology and Function in Experimental Diabetes

Table 3

Effects of OPLE on renal structure.

	Nondiabetic	Diabetic control	Diabetic + OPLE	Diabetic + OPLE
			200 mg kg^−1	500 mg kg^−1
	(4 week)	(4 week)	(4 week)	(4 week)
	(12 week)	(12 week)	(12 week)	(12 week)
Glomerulosclerotic index	0.23 ± 0.03	1.14 ± 0.06^aa	0.89 ± 0.07^aa	0.79 ± 0.5^aa,b
	0.34 ± 0.03	1.36 ± 0.04^aa	0.93 ± 0.05^aa,b	0.88 ± 0.04^aa,b
Tubulointerstitial fibrosis index	0.49 ± 0.05	2.48 ± 0.18^aa	1.48 ± 0.06^a,b	1.16 ± 0.03^b
	0.61 ± 0.06	2.75 ± 0.16^a	1.31 ± 0.23^b	1.05 ± 0.14^b

Data are expressed as mean ± SEM of six experiments for each group. ^a𝑃<0.05,^aa𝑃<0.01 versus corresponding nondiabetic; ^b𝑃<0.05 versus corresponding diabetic control.