Research Article

Long-Term Oral Administration of Capsicum baccatum Extracts Does Not Alter Behavioral, Hematological, and Metabolic Parameters in CF1 Mice

Table 3

Serum biochemical evaluations of mice following gavage administration of C. baccatum extracts for 60 days (200 mg/kg).

ParametersControlEthanolButanol

ALT (IU/L)29.0 ± 10.9445.8 ± 40.5242.2 ± 18.79
ALP (IU/L)45.7 ± 21.7428.5 ± 15.9341.3 ± 14.68
Proteins (mg/dL)4.9 ± 0.584.9 ± 0.424.8 ± 0.38
Albumin (mg/dL)2.0 ± 0.452.0 ± 0.211.6 ± 0.38
LDH (IU/L)150.2 ± 37.2202.2 ± 83.93148.0 ± 22.43
Triglycerides (mg/dL)91.0 ± 25.6376.4 ± 21.97102.2 ± 31.42
Cholesterol (mg/dL)129.5 ± 9.93101.0 ± 13.58119.4 ± 26.81
HDL-cholesterol (mg/dL) 63.5 ± 8.6853.3 ± 7.6956.7 ± 10.08
LDL-cholesterol (mg/dL)47.8 ± 11.2832.4 ± 11.0842.3 ± 24.55
Glucose (mg/dL)96.2 ± 44.45133.5 ± 47.53108.6 ± 34.70
Urea (mg/dL)42.5 ± 3.1545.6 ± 1.5245.3 ± 12.53
Creatinine (mg/dL)<0.200.20 ± 0.04<0.20

ALT: alanine aminotransferase; ALP: alkaline phosphatase; LDH: lactate dehydrogenase. Neither of the treated groups was significantly different from the control group. Values are means ± SEM of 10 animals. No significant difference was observed among groups ( ).