Are the Adaptogenic Effects of Omega 3 Fatty Acids Mediated via Inhibition of Proinflammatory Cytokines?

Table 3

Three regression models testing for mediation effects.

		Independent variable	Beta	t	Sig.
Direct effects	Model 1	AA	−0.185	−1.715	0.088
	Dependent Variable: CopingAve	DHA	0.127	1.176	0.241
Indirect (mediated) effects	Model 2	AA	0.326	3.085	0.002
	Dependent Variable: CytokineAve	DHA	−0.169	−1.601	0.111
	Model 3
	Dependent Variable: CopingAve	CytokineAve	−0.098	−1.365	0.174

n = 194; composite score for CytokineAve and CopingAve computed by averaging across items in respective factors (unit-weighted); AA = red blood cell membrane phospholipid arachidonic acid, measured in micrograms per millilitre of blood (μg/mL); DHA = red blood cell membrane phospholipid docoxahexaenoic acid, measured in micrograms per millilitre of blood (μg/mL).