Hepatoprotective Activity of the Total Saponins from Actinidia valvata Dunn Root against Carbon Tetrachloride-Induced Liver Damage in Mice

Table 2

Effects of TSAV on serum enzyme activities with CCl₄-induced hepatic damage in mice.

Group	AST (IU/L)	ALT (IU/L)	ALP (IU/L)
I	58.71^a±17.02	24.10^a±3.72	139.58^a±15.53
II	1724.82^d±478.62	4112.02^d±1062.96	250.12^c±14.99
III	1250.11^c±334.93	2583.45^c±426.52	217.23^b±23.71
IV	1164.23^c±259.20	2563.52^c±401.25	194.98^b±18.39
V	901.60^b±231.51	2231.91^b±407.22	151.08^a±07.41
VI	1190.54^c±262.20	2533.93^c±446.91	166.78^a±13.84

Group I: control; Group II: CCl₄; Group III: TSAV 50 mg/kg + CCl₄; Group IV: TSAV 100 mg/kg + CCl₄; Group V: TSAV 200 mg/kg + CCl₄; Group VI: silymarin 200 mg/kg + CCl₄.
Values are given as mean ± SD (𝑛 = 10 mice/group); means with different alphabets differ significantly at 𝑃<0.05 level.