Hepatoprotective Activity of the Total Saponins from Actinidia valvata Dunn Root against Carbon Tetrachloride-Induced Liver Damage in Mice

Table 3

Effects of TSAV on liver lipid peroxidation and antioxidant enzymes with CCl₄-induced hepatic damage in mice.

Group	MDA^A	SOD^B	CAT^C	GPX^D	GR^E	GSH^F	GSSG^G	GSH/GSSG
I	0.82^a±0.04	35.71^b±3.60	382.72^e±22.79	247.35^d±42.21	7.56^c±1.25	6.02^d±0.55	0.39^a±0.05	15.75^f±3.12
II	1.81^c±0.15	26.12^a±0.82	218.86^a±44.95	153.31^a±26.34	5.12^a±0.66	4.12^a±0.79	0.78^d±0.11	5.40^a±1.28
III	1.69^c±0.22	29.16^a±2.50	241.06^b±36.12	180.66^b±24.72	5.87^b±0.93	4.62^b±0.87	0.68^c±0.14	6.84^b±0.98
IV	1.13^b±0.11	35.32^b±3.13	252.74^b±32.43	207.92^c±18.37	6.24^b±1.02	4.88^b±0.76	0.64^c±0.05	7.65^c±0.81
V	0.93^a±0.08	42.87^c±3.61	324.78^d±25.19	236.84^d±29.52	7.31^c±1.21	5.64^c±0.47	0.53^b±0.09	10.96^e±2.08
VI	1.25^b±0.18	32.04^b±2.05	289.45^c±33.94	230.11^d±21.26	7.24^c±0.82	5.34^c±0.38	0.58^b±0.06	9.25^d±1.10

Group I: control; Group II: CCl₄; Group III: TSAV 50 mg/kg + CCl₄; Group IV: TSAV 100 mg/kg + CCl₄; Group V: TSAV 200 mg/kg + CCl₄; Group VI: silymarin 200 mg/kg + CCl₄.
^Anmol/mg protein, ^BU/mg protein, ^CU/g protein, ^DU/mg protein, ^EU/g protein,^F,Gμmol/g protein. Values are given as mean ± SD (𝑛=10 mice/group); means with different alphabets differ significantly at 𝑃<0.05 level.