Propolis Prevents Hepatorenal Injury Induced by Chronic Exposure to Carbon Tetrachloride

Table 2

Potential of propolis in maintaining metabolizing enzymes. (Values are mean ± SE from six rats in each group.)

Groups	Adenosine triphosphatase		Acid phosphatase		Alkaline phosphatase
	(mg Pi/100 mg/min)		(mg Pi/100 mg/h)		(mg Pi/100 mg/h)
	Hepatic	Renal	Hepatic	Renal	Hepatic	Renal
Control	2020 ± 111	2500 ± 138	250 ± 30.9	270 ± 14.9	74.0 ± 4.09	2580 ± 142
CCl4	987 ± 54.5^#	1095 ± 60.5^#	1395 ± 77.1^#	1440 ± 79.6^#	36.0 ± 1.99^#	716 ± 39.6^#
CCl4 + Propolis	1742 ± 96.2*	1775 ± 98.1*	338 ± 18.7*	378 ± 20.9*	68.0 ± 3.75*	1591 ± 87.9*
% Protection	73.1%	48.4%	92.3%	90.7%	84.2%	46.9%
CCl4 + Silymarin	1806 ± 99.8*	1880 ± 232*	335 ± 18.5*	342 ± 18.9*	69.0 ± 3.81*	1665 ± 92.1*
% Protection	79.3%	55.8%	92.6%	93.8%	86.8%	50.9%
F Variance	28.1^†	36.7^†	208^†	202^†	29.3^†	73.1^†

𝑃 value CCl₄ versus control at #≤0.05; therapy versus CCl₄ at ∗≤0.05; ^†significant for analysis of variance 𝑃≤0.05.