Research Article

Propolis Prevents Hepatorenal Injury Induced by Chronic Exposure to Carbon Tetrachloride

Table 3

Effect of propolis on hepatorenal biochemical assay against carbon tetrachloride intoxication. (Values are mean ± SE from six rats in each group.)

GroupsTotal protein contentsGlycogen contentsTriglycerides
(mg/100 mg)(mg/100 g)(mg/100 mg)
HepaticRenalHepaticRenalHepaticRenal

Control15.7 ± 0.8615.1 ± 0.832700 ± 14984.0 ± 4.643.20 ± 0.172.95 ± 0.16
CCl412.3 ± 0.67#13.1 ± 0.72#984 ± 54.3#51.1 ± 2.81#8.30 ± 0.45#6.78 ± 0.37#
CCl4 + Propolis15.3 ± 0.84*14.1 ± 0.77*2128 ± 117*79.0 ± 4.36*3.80 ± 0.21*3.37 ± 0.18*
% Protection88.2%50.0%66.6%84.8%88.2%89.1%
CCl4 + Silymarin15.4 ± 0.85*14.3 ± 0.79*2240 ± 123*81.0 ± 4.47*3.60 ± 0.19*3.58 ± 0.19*
% Protection91.1%60.0%73.1%90.9%92.2%83.5%

F Variance4.581.3246.916384.661.6

value CCl4 versus control at ; therapy versus CCl4 at ; significant for analysis of variance .