Research Article
Treatment of Common Cold Patients with the Shi-Cha Capsule: A Multicenter, Double-Blind, Randomized, Placebo-Controlled, Dose-Escalation Trial
Table 4
Intent-to-treat and per-protocol analyses of main symptom score, minor symptom score, and cumulative symptom score.
| Intent-to-treat analysis | Change from baseline to day 4 (mean ± SD) | Group A (n = 114) | Group B (n = 117) | Group C (n = 115) |
| Main symptom score | 8.842 ± 3.453 | 8.513 ± 3.050 | 7.330 ± 4.209 | P value versus group C | <0.0001 | <0.0001 | | Minor symptom score | 5.851 ± 2.839 | 6.120 ± 2.443 | 5.157 ± 2.648 | P value versus group C | <0.0001 | <0.0001 | | Cumulative symptom score | 14.320 ± 5.577 | 13.890 ± 4.949 | 11.920 ± 6.090 | P value versus group C | <0.0001 | <0.0001 | |
| Per-protocol analysis | Group A (n = 113) | Group B (n = 113) | Group C (n = 108) |
| Main symptom score | 8.920 ± 3.365 | 8.522 ± 3.094 | 7.417 ± 4.212 | P value versus group C | <0.0001 | <0.0001 | | Minor symptom score | 5.876 ± 2.838 | 6.053 ± 2.394 | 5.241 ± 2.696 | P value versus group C | <0.0001 | <0.0001 | | Cumulative symptom score | 14.420 ± 5.498 | 13.850 ± 5.016 | 12.060 ± 6.143 | P value versus group C | <0.0001 | <0.0001 | |
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