Hypoglycemic and Hypolipidemic Effects of Ethanolic Extract of Mirabilis jalapa L. Root on Normal and Diabetic Mice

Table 2

Effects of single and repeated EEM administration on serum TC and TG levels in normal and diabetic mice.

Group	Single administration		Repeated administration
	TC (mmol/L)	TG (mmol/L)	TC (mmol/L)	TG (mmol/L)
Normal control	2.13±0.20	0.74±0.07	2.13±0.16	0.75±0.06
Normal + 2 g/kg EEM	2.11±0.20	0.75±0.11	2.14±0.17	0.75±0.06
Normal + 4 g/kg EEM	2.17±0.22	0.77±0.09	2.14±0.20	0.74±0.05
Normal + 8 g/kg EEM	2.08±0.22	0.75±0.08	2.10±0.16	0.73±0.06
Normal + glibenclamide	2.11±0.21	0.75±0.08	2.11±0.14	0.74±0.08
Diabetic control	3.47±0.33 *	1.26±0.12 *	3.49±0.32 *	1.28±0.09 *
Diabetic + 2 g/kg EEM	3.45±0.39	1.24±0.10	3.47±0.26	1.24±0.11
Diabetic + 4 g/kg EEM	3.44±0.43	1.24±0.12	2.92±0.22^#	1.01±0.11^#
Diabetic + 8 g/kg EEM	3.44±0.31	1.25±0.10	2.82±0.25^#	0.97±0.07^#
Diabetic + glibenclamide	3.48±0.34	1.23±0.10	3.46±0.13	1.27±0.09

Data are expressed as mean ± SD, 𝑛=10 mice per group. *𝑃<0.01 when compared to normal control. ^#𝑃<0.01 when compared to diabetic control.