Research Article

A Chan Dietary Intervention Enhances Executive Functions and Anterior Cingulate Activity in Autism Spectrum Disorders: A Randomized Controlled Trial

Figure 2

(a) Graphical representation of LORETA independent t-statistics results adopted from the research article by Chan et al. [43] published in the Research in Autism Spectrum Disorders. The location of the voxel is defined by the Talairach coordinates (X, Y, Z), and the regions colored in red represent significant hypoactivity in the anterior cingulate cortex (ACC, in the circle) of children with autism spectrum disorders (ASDs) as compared to their normal counterparts (NCs) during the Go and No-go conditions. (b) Graphical representation of LORETA paired -statistics results that compares the pre- and post-one-month theta source activity of the control and experimental groups during the Go and No-go conditions. The regions colored in blue indicate significantly elevated ACC activity after one month at (one-tailed) < 0.05. The ACC regions (in the circle), in which hypoactivity was previously found in children with autism spectrum disorders, were enhanced in activity after diet modification in the experimental group.
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