Ginseng and Its Active Components Ginsenosides Inhibit Adipogenesis in 3T3-L1 Cells by Regulating MMP-2 and MMP-9
Figure 7
Effects of MMP regulators on adipogenesis in 3T3-L1 cells. (a) Effects of galardin on lipid accumulation. 3T3-L1 preadipocytes were differentiated into mature adipocytes. Cells were treated with different concentrations of galardin on days 0–2 only during the differentiation process. (b) Effects of GE and GSs on PMA-induced lipid accumulation in 3T3-L1 cells. Cells were treated with MDI (control), MDI plus GE, TGSs, or Rb1 in the absence or presence of PMA on days 0–2 only during the differentiation process. At day 8 after induction, cells were fixed, and neutral lipids were stained with Oil Red O. Con: differentiated control; GE: ginseng extract; TGSs: total ginsenosides; PMA: phorbol 12-myristate 13-acetate.
