Myrrh Inhibits LPS-Induced Inflammatory Response and Protects from Cecal Ligation and Puncture-Induced Sepsis
Effects of myrrh on CLP-induced liver damage. Myrrh (0.1 g/kg or 0.2 g/kg) was administrated intraperitoneally 1 h before CLP. (a) Representative H&E-stained sections of liver in mice given saline or myrrh (0.1 or 0.2 mg/kg) 1 h before CLP. 24 h after CLP, mice were sacrificed, then liver and blood were harvested. (b) Liver neutrophil infiltration was assessed by MPO activity. (c) The ALT and AST levels were measured in serum using biochemical kits as described in Subjects and Methods. (d) mRNA levels of cytokines were measured in liver by RT-PCR. The values are means ± SD of three independent experiments. * versus saline. + versus LPS.