Traditional Herbal Medicine, Rikkunshito, Induces HSP60 and Enhances Cytoprotection of Small Intestinal Mucosal Cells as a Nontoxic Chaperone Inducer
TUNEL staining. (a); IEC-6 cells treated with hydrogen peroxide or indomethacin showed typical morphological features of apoptotic cells with condensed and fragment nuclei. When IEC-6 cells were pretreated with TJ-43, apoptosis was apparently suppressed. (b); Ratio of apoptotic cells significantly reduced in IEC-6 cells treated with TJ-43 compared with control cells (untreated IEC-6 cells). Values are means ± SEM. *, ** compared with control cells (IEC-6-mock cells).
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