Research Article

Comprehensive Evaluation of Anti-hyperglycemic Activity of Fractionated Momordica charantia Seed Extract in Alloxan-Induced Diabetic Rats

Table 3

Effect of prolonged Mc-3 treatment on serum glucose levels.

Period (days) of treatment03691218

PBS-treated normal
PBS-treated diabetic
Mc-3-treated diabetic
Insulin-treated diabetic

Diabetic animals ( ) were administered with Mc-3 (15 mg/kg b.wt.) in PBS or protamine zinc insulin (10 IU/kg b.wt.) once daily. Fasting serum glucose levels (mg/dL) were measured on the days indicated. Control diabetic animals ( ) were treated with equal volume of PBS. The data represent mean ± S.D. ; ; , compared with serum glucose levels on 0 day.