Intestinal, Airway, and Cardiovascular Relaxant Activities of Thymoquinone
Figure 4
Typical tracing showing the relaxant effect of thymoquinone on high K+-(80 mM) and carbachol- (CCh, 1 M) induced contractions in isolated rabbit trachea preparation (a); upper tracing provides a time control. Pooled data for this relaxant effect of the compound on high K+-(80 mM) and carbachol-(CCh, 1 M) induced contractions is shown in (b). Also shown in (b) is the effect of thymoquinone in the absence and presence of propranolol-(1 M) on CCh-(1 M) induced contractions. Values shown are mean ± SEM, = 3–5; there is no difference between the curves (), but there is a significant difference between individual concentrations in all the curves (), two-way ANOVA.
