Intestinal, Airway, and Cardiovascular Relaxant Activities of Thymoquinone
Figure 5
Airway contractile effect of acetylcholine (ACh). Images showing the progressive airway contractile effect of ACh (from left to right), shown in a series of (a) transmitted light (upper panel) and (b) fluorescent (lower panel) images. Note the decrease in the size of airway lumen (AL) in response to ACh administration in the upper panel. White arrows show appearance of bright fluorescent bands (airway smooth muscles) around the airway after ACh administration. Last column shows that the airway diameter and brightness (Ca++ levels) return to the baseline after washing the lung slice with physiological salt solution. Time course for the effect of ACh on airway contraction to washout is 2 min.
