Intestinal, Airway, and Cardiovascular Relaxant Activities of Thymoquinone
Figure 8
Graph showing concentration-dependent relaxant effect of thymoquinone on high K+-(80 mM) and phenylephrine-(PE, 1 M) induced contractions in isolated endothelium-intact rat aorta. Graph also shows vasodilator effect of thymoquinone in the absence and presence of atropine (1 M) and L-NAME (0.1 mM) on PE-(1 M) induced contractions. Values shown are mean ± SEM, = 4-5; there is a significant difference between the two curves with “bold symbols” (), while no difference between all the three PE curves (). There is a significant difference between individual concentrations in all the curves (), two-way ANOVA.
