Pharmacokinetics and Relative Bioavailability of Flavonoids between Two Dosage Forms of Gegen-Qinlian-Tang in Rats

Table 3

Comparison of bioavailabilities of flavonoids from GQT, PR and SR in rats.

Flavonoids	Treatments	AUC0−𝑡; (mean ± S.E.)	Dose; (μmol/kg)	AUC0−𝑡/dose
Daidzin/daidzein	GQT (𝑛=6)	11.3±1.5	35.2	0.32±0.04
	PR (𝑛=7)	8.9±1.1	26.6	0.33±0.04
Baicalin/baicalein	GQT (𝑛=6)	5.0±1.3	193.0	0.03±0.01
	SR (𝑛=6)	4.2±0.7	250.9	0.02±0.00

AUC_0−𝑡 (μmol·min/mL): area under the serum concentration-time curve of sulfates/glucuronides of daidzein and baicalein from zero to the last point.