Research Article

MART-10, a New Generation of Vitamin D Analog, Is More Potent than 1α,25-Dihydroxyvitamin D3 in Inhibiting Cell Proliferation and Inducing Apoptosis in ER+ MCF-7 Breast Cancer Cells

Table 1

The distribution of different phases of MCF-7 cell cycle under the influence of 1α,25(OH)2D3 or MART-10.

  G1 S G2/M

Control50.36%33.51%16.13%
1,25D*, 10−8 M56.17%30.06%13.77%
1,25D, 10−7 M63.70%23.85%12.36%
1,25D, 10−6 M64.14%21.96%13.90%
M-10#, 10−9 M60.81%23.65%15.54%
M-10, 10−8 M65.72%21.32%12.96%
M-10, 10−7 M70.29%12.98%16.73%

*1,25D: 1 ,25(OH)2D3.
#M-10: MART-10.