Research Article

Reversal of the Caspase-Dependent Apoptotic Cytotoxicity Pathway by Taurine from Lycium barbarum (Goji Berry) in Human Retinal Pigment Epithelial Cells: Potential Benefit in Diabetic Retinopathy

Figure 1

Time- and dose-dependent effect on cell viability following LB extract (a) and taurine (b) treatment. ARPE-19 cells were seeded onto 96-well plates, and LB extract (0.001, 0.01, 0.1, 0.5, 1, and 5 mg/mL) and taurine (0.001, 0.01, 0.1, 5, and 10 mM) were added to the medium for 24, 48, and 72 h. Cell viability was measured by MTS assay. The values of cell viability were normalised to the value of the control. The data represents the mean ± SEM of 5 independent experiments. Rosiglitazone (RG) served as positive control, and colchicine (Colch) served as negative control.
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(a)
323784.fig.001b
(b)