Research Article

Dry Needling at Myofascial Trigger Spots of Rabbit Skeletal Muscles Modulates the Biochemicals Associated with Pain, Inflammation, and Hypoxia

Figure 6

The variation in TNF- after one- and five-dosage dry needling (1D, 5D) in the biceps femoris with a taut band in the experimental (1D, 5D) and sham groups (s1D, s5D). Representative photomicrographs indicate the immunohistochemical labeling for TNF- in the muscle immediately after dry needling: (a) s1D, (b) 1D, (c) s5D, and (d) 5D, as well as 5 d after dry needling: (e) s1D, (f) 1D, (g) s5D, and (h) 5D. Histograms indicate the quantitative analysis of (i) TNF-LI cells and (j) protein levels of TNF- by applying ELISA in the serum. *Indicates the significant difference ( ) between the sham groups (s1D and s5D). #Represents the significant difference ( ) between the 1D and 5D groups. DN: dry needling. (scale bar = 5 μm).
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