Anti-Hepatitis B Virus Effect and Possible Mechanism of Action of 3,4-O-Dicaffeoylquinic Acid In Vitro and In Vivo

Table 3

Cytotoxicity of 3,4-dicaffeoylquinic acid in hepG2.2.15 cells.

Groups	Concentration (μg/mL)	Absorbency (570 nm)	Cell survival (%)
Vehicle	—	0.922±0.031	100
Lamivudine	100	0.906±0.101	98.26
	50	0.912±0.092	98.92
	10	0.918±0.141	99.57
3,4-Dicaffeoylquinic acid	100	0.893±0.061	96.85
	50	0.895±0.105	97.07
	10	0.909±0.078	98.59

All determinations were performed in six replicates, and values were expressed as mean ± SD. No significant difference compared with the vehicle control.