Inhibitory Effects of Daiokanzoto (Da-Huang-Gan-Cao-Tang) on P-Glycoprotein

<table>Inhibitory effects of rhubarb on ATPase activity in the presence of verapamil. Rhubarb was added to a final concentration of 0 (●), 0.0625 (○), 0.25 (▲), or 0.5 (<svg height="10.6625" id="M39" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 11.4125 10.6625" width="11.4125" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,10.6625)">
<g transform="translate(72,-63.47)">
<text transform="matrix(1,0,0,-1,-71.95,63.52)">
<tspan style="font-size: 12.50px; " x="0" y="0">Δ</tspan>
</text>
</g>
</g>
</svg>) mg/mL together with various concentrations of verapamil. Data represent the mean <svg height="9.3249998" id="M40" style="vertical-align:-1.09097pt" version="1.1" viewbox="0 0 10.825 9.3249998" width="10.825" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,9.325)">
<g transform="translate(72,-64.54)">
<text transform="matrix(1,0,0,-1,-71.95,65.67)">
<tspan style="font-size: 12.50px; " x="0" y="0">±</tspan>
</text>
</g>
</g>
</svg> SD of three experiments.</table>

Evidence-Based Complementary and Alternative Medicine

fig5

Figure 5

Figure 5: Inhibitory Effects of Daiokanzoto (Da-Huang-Gan-Cao-Tang) on P-Glycoprotein 