Wnt-Signaling-Mediated Antiosteoporotic Activity of Porcine Placenta Hydrolysates in Ovariectomized Rats

Table 2

Body weights, peri-uterine and retroperitoneal fat weights, uterus weights, and serum 17β-estradiol levels at the end of the 12-week study period.

	OVX-control	OVX-WPPH	OVX-NPPH	OVX-EST	Sham-control
	(𝑛=10)	(𝑛=10)	(𝑛=10)	(𝑛=10)	(𝑛=10)
Body weight (g)	329 ± 25^a	313 ± 24^ab	297 ± 23^b	274 ± 25^c*	271 ± 23^†
Peri-uterine fat (g)	6.4 ± 0.8^a	5.8 ± 0.7^ab	5.2 ± 0.7^b	4.3 ± 0.5^c*	3.9 ± 0.5^††
Retroperitoneum fat (g)	8.8 ± 1.0^a	8.1 ± 0.9^ab	7.2 ± 0.8^b	6.1 ± 0.7^c*	5.4 ± 0.7^††
Uterus weight (g)	1.3 ± 0.2^b	1.4 ± 0.2^ab	1.6 ± 0.3^a	1.8 ± 0.3^a*	1.9 ± 0.3^†
Uterus index (mg/g)	4.0 ± 0.5^b	4.5 ± 0.6^ab	5.5 ± 0.8^b	6.5 ± 0.9^c*	7.0 ± 0.9^††
Serum 17β-estradiol (pg/mL)	9.6 ± 1.1	9.8 ± 1.0	10.8 ± 1.3	24.8 ± 3.9^a*	20.3 ± 3.2^†††

Uterus index was calculated as uterus weight divided by body weight.
Values are mean ± SD. *Significantly different among the different treatments in OVX rats at P < 0.05. ^a,b,cValues with different superscripts were significantly different among the OVX groups by Tukey’s test at P < 0.05. ^†Significantly different between OVX-control and Sham-control at P < 0.05, ^††P < 0.01, ^†††P < 0.001.