371286.fig.005a
(a)
371286.fig.005b
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371286.fig.005c
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Figure 5: Effect of GTE on the mitochondria/caspase pathway in H23/0.3 cells. (a) H23/0.3 cells were treated with various concentrations of GTE (0 mg/mL, 0.3 mg/mL, and 0.9 mg/mL) for 24 h. The protein expression of Bcl-2 and Bax was measured by western blotting. (b) H23/0.3 cells were treated with various concentrations of GTE (0 mg/mL, 0.3 mg/mL, and 0.9 mg/mL) for 24 h. The release of cytochrome c (Cyt-c) into the cytoplasm was detected by western blotting. (c) H23/0.3 cells were treated with various concentrations of GTE (0 mg/mL, 0.3 mg/mL, and 0.9 mg/mL) for 24 h. The cleavage of caspase-3 and PARP was detected by western blotting. Results are expressed as the mean ± SD of three independent experiments.