Luteolin Suppresses Inflammatory Mediator Expression by Blocking the Akt/NFκB Pathway in Acute Lung Injury Induced by Lipopolysaccharide in Mice

Figure 4

Effect of luteolin on LPS-induced iNOS and COX-2 expression in lung. Lungs were harvested from posttreated mice and whole tissue extracts were subjected to SDS-PAGE Western blot analysis using antibodies for iNOS, COX-2, and GAPDH. The ratio of immunointensity between iNOS/GAPDH and COX-2/GAPDH was calculated. The fold increases in the immunointensity is expressed as means ± S.D. (𝑛=3–5 in each group). *𝑃<0.05 versus control; ^#𝑃<0.05 versus LPS group.

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