Research Article
Single Agent Polysaccharopeptide Delays Metastases and Improves Survival in Naturally Occurring Hemangiosarcoma
Table 3
Median and range blood chemistry values for 15 dogs with hemangiosarcoma treated with 25, 50, or 100 mg/kg/day I'm-Yunity (polysaccharopeptide).
| | Normal values | 25 mg/kg/day | 50 mg/kg/day | 100 mg/kg/dy | Baseline
() | Week 3
() | Week 7
() | Baseline
() | Week 3
() | Week 7
() | Baseline
() | Week 3
() | Week 7
() |
| Glucose
65–112 mg/dl | 79
(73–122) | 88
(77–106) | 91
| 101
(87–121) | 100
(84–108) | 100
(96–103) | 87
(75–101) | 96
(86–126) | 91
(90–92) | BUN
5–30 mg/dl | 17
(10–26) | 25
(13–31) | 27
| 18
(17–23) | 19
(15–25) | 19
(18–20) | 25
(18–55) | 27
(20–34) | 26
(17–39) | Creatinine
0.7–1.8 mg/dl | 0.9
(0.7–1.5) | 1.4
(0.6–1.8) | 1.9 | 1.0
(0.9–1.3) | 1.0
(0.9–1.5) | 1.0
(0.8–1.2) | 1.2
(0.8–1.5) | 1.2
(1.1–1.2) | 1.0
(0.9–1.3) | Calcium
9.8–11.7 mg/dl | 10.4
(9.7–12.0) | 10.3
(9.1–12.0) | 12.0 | 9.7
(9.6–11.0) | 10.2
(9.8–10.8) | 10.0
(9.6–10.3) | 10.2
(9.6–10.7) | 10.2
(9.1–11.4) | 10.1
(10.1–10.7) | Sodium
140–150 nmol/L | 144
(132–148) | 141
(138–146) | 141 | 146
(139–147) | 144
(143–147) | 143
(142–143) | 146
(143–146) | 146
(140–152) | 146
(143–146) | Potassium
4.0–5.2 nmol/L | 4.9
(4.6–5.4) | 4.4
(3.4–5.1) | 5.1 | 4.6
(4.4–5.6) | 4.5
(3.7–4.6) | 4.4
(4.1–4.7) | 4.8
(4.0–5.0) | 4.8
(3.5–5.6) | 4.6
(4.5–5.1) | Total protein
5.4–7.1 g/dl | 6.3
(5.6–6.7) | 6.0
(4.4–7.0) | 5.5 | 6.0
(5.3–7.0) | 5.9
(5.6–6.3) | 5.8
(5.7–5.9) | 5.9
(5.7–6.4) | 6.1
(4.8–6.5) | 6.4
(6.3–6.5) | Albumen
2.5–3.7 g/dl | 3.0
(2.8–3.3) | 3.0
(2.2–3.8) | 3.2 | 3.2
(3.0–4.0) | 3.1
(2.9–3.5) | 3.3
(3.2–3.4) | 3.0
(2.9–3.5) | 3.0
(2.5–3.4) | 3.2
(3.1–3.4) | Globulin
2.4–4.0 g/dl | 3.2
(2.8–3.6) | 3.0
(2.2–3.2) | 2.3 | 2.8
(2.2–3.4) | 2.7
(2.5–3.1) | 2.5
(2.3–2.7) | 2.8
(2.3–3.3) | 3.1
(2.1–3.2) | 3.1
(3.1–3.3) | ALT
16–91 U/L | 32
(13–57) | 46
(20–89) | 32
| 60
(13–102) | 49
(27–64) | 89
(33–145) | 59
(14–159) | 62
(46–118) | 36
(26–60) | SAP
20–155 U/L | 143
(59–346) | 148
(55–575) | 105 | 83
(29–828) | 79
(41–688) | 461
(49–872) | 112
(37–156) | 82
(47–184) | 131
(93–166) | | Total bilirubin 0.1–0.5 mg/dl | 0.1
(0.1–0.3) | 0.2
(0.1–0.2) | 0.5 | 0.3
(0.1–0.9) | 0.1
(0.1–0.2) | 0.3
(0.2–0.3) | 0.1
(0.1–0.5) | 0.2
(0.1–0.3) | 0.2
(0.2–0.3) | Cholesterol
128–317 mg/dl | 260
(161–292) | 300
(138–393) | 343 | 247
(181–258) | 233
(186–274) | 242
(156–328) | 220
(196–276) | 260
(165–492) | 332
(285–442) |
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