Research Article
Single Agent Polysaccharopeptide Delays Metastases and Improves Survival in Naturally Occurring Hemangiosarcoma
Table 4
Median and range complete blood count values for 15 dogs with hemangiosarcoma treated with 25, 50, or 100 mg/kg/day I'm-Yunity (polysaccharopeptide).
| | Normal values | 25 mg/kg/day | 50 mg/kg/day | 100 mg/kg/dy | Baseline
() | Week 3
() | Week 7
() | Baseline
() | Week 3
() | Week 7
() | Baseline
() | Week 3
() | Week 7
() |
| Red blood cells
5.9–8.9 × 106 /μl | 5.3
(4.8–6.2) | 4.3
(3.1–5.7) | 4.3 | 5.8
(5.5–6.4) | 6.0
(4.7–6.4) | 4.2
(3.5–5.0) | 5.2
(5.0–5.6) | 5.7
(2.0–6.0) | 5.4
(5.3–5.8) | Hemoglobin
13.3–20.5 g/dl | 12.6
(11.4–14.4) | 10.4
(7.0–13.4) | 10.8 | 12.9
(12.2–14.3) | 13.1
(10.3–14.3) | 8.9
(7.2–10.7) | 12.7
(11.8–17.0) | 14.3
(4.7–14.9) | 13.7
(13.4–14.6) | Hematocrit
40.3–60.3 % | 36.2
(32.9–40.3) | 29.4
(20.7–39.7) | 30.8 | 37.1
(35.0–39.4) | 37.5
(30.0–40.1) | 26.2
(21.2–31.2) | 35.4
(34.3–39.4) | 40.7
(13.7–42.1) | 37.8
(37.2–41.0) | Platelets
177–398 × 103/μl | 639
(363–785) | 422
(107–642) | 536 | 441
(120–682) | 272
(122–386) | 117
(116–117) | 577
(180–746) | 569
(92.1–640) | 532
(491–625) | White blood cell
5.3–19.8 × 103/μl | 10.2
(9.1–12.5) | 7.7
(5.6–29.4) | 9.3 | 8.2
(7.0–15.8) | 10.6
(6.9–13.3) | 12.4
(8.1–16.7) | 9.7
(6.9–11.8) | 11.0
(8.3–23.2) | 9.9
(9.7–13.2) | Neutrophils
3.1–14.4 × 103/μl | 6.7
(6.1–8.6) | 5.6
(4.3–26.2) | 7.9 | 6.5
(4.8–14.1) | 7.7
(4.5–12.0) | 10.8
(6.5–15.0) | 6.5
(5.0–10.2) | 9.2
(6.2–20.0) | 7.4
(7.2–9.2) | Lymphocytes
0.9–5.5 × 103/μl | 1.9
(0.7–2.8) | 1.0
(0.8–1.2) | 0.8 | 0.8
(0.5–1.3) | 0.7
(0.1–1.8) | 0.7
(0.3–1.1) | 0.9
(0.6–1.7) | 1.7
(0.3–2.2) | 2.0
(1.8–2.6) | Monocytes
0.1–1.4 × 103/μl | 0.7
(0.5–1.3) | 0.5
(0.3–2.1) | 0.4 | 0.6
(0.4–1.0) | 0.7
(0.3–1.4) | 0.7
(0.5–1.0) | 0.5
(0.1–0.7) | 0.4
(0.3–0.7) | 0.5
(0.2–0.8) | Eosinophils
0.0–1.6 × 103 /μl | 0.7
(0.2–1.3) | 0.4
(0.1–0.9) | 0.2 | 0.3
(0.2–1.4) | 0.5
(0.1–0.8) | 0.1
(0.1–0.2) | 0.4
(0.2–0.8) | 0.5
(0.3–0.6) | 0.3
(0.2–0.5) |
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