Inhibition of Hypoxia Inducible Factor Alpha and Astrocyte-Elevated Gene-1 Mediates Cryptotanshinone Exerted Antitumor Activity in Hypoxic PC-3 Cells

Figure 6

Effect of CT on the biomarkers of Ki-67, AEG-1, VEGF, CD34, and CAIX by immunohistochemistry. Immunohistochemistry was performed in tumor sections with antibodies of Ki-67 for proliferation, VEGF for angiogenesis, CD34 for microvessel density, CAIX for hypoxia, and AEG-1. The photographs were taken at ×200 magnification.