Drug-Drug Interactions Potential of Icariin and Its Intestinal Metabolites via Inhibition of Intestinal UDP-Glucuronosyltransferases
Figure 2
Representative Lineweaver-Burk plots (a) and Dixon plots (b) of the effects of icariin on 4-MU glucuronide formation in recombinant UGT1A3. Reactions were performed as described in Materials and Methods. All data points shown represent the mean of duplicate measurements.