Drug-Drug Interactions Potential of Icariin and Its Intestinal Metabolites via Inhibition of Intestinal UDP-Glucuronosyltransferases
Figure 3
Representative Lineweaver-Burk plots (a, c, e) and Dixon plots (b, d, f) of the effects of icariside II on UGT1A4 (a and b), UGT1A7 (c and d), and UGT2B7 (e and f) in recombinant UGTs. Reactions were performed as described in Materials and Methods. All data points shown represent the mean of duplicate measurements.
