Efficacy of Bidens pilosa Extract against Herpes Simplex Virus Infection In Vitro and In Vivo
Cytotoxic and virucidal effects of the extract of B. pilosa. (a) Cell viability was determined in triplicate cultures by WST-8 assay. The results are expressed as percentage of control and are mean ± SD of triplicate cultures. (b) Effects of the extract of B. pilosa on HSV-1 and HSV-2 infectivity. Viruses were incubated for 1 h at 37°C with increasing concentrations of the extract and immediately tested in a plaque reduction assay. Data are presented as % of control. Data are mean ± SD of triplicate cultures.