Apoptosis Induction in Primary Human Colorectal Cancer Cell Lines and Retarded Tumor Growth in SCID Mice by Sulforaphane
Figure 4
Reduction of the mitochondrial membrane potential in the CRC cell lines by SFN, which was determined by JC-1 staining and detected by the flow cytometry. (a) Dot plots of five CRC cell lines with SFN treatment at 0, 6.25, 12.5, and 25 μM for 6 h. (b) The reduction of the containing polarized or depolarized mitochondria determined the ratio of the two fluorescence intensities analyzed by flow cytometry. All the data shown are the folds of five CRC cell lines. The symbol (*) on each group of bars denotes that difference from the treatment with 0 μM SFN is statistically significant at .
