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Evidence-Based Complementary and Alternative Medicine
Volume 2012 (2012), Article ID 428560, 10 pages
Research Article

Herb-Drug Interaction of Paullinia cupana (Guarana) Seed Extract on the Pharmacokinetics of Amiodarone in Rats

1Laboratory of Pharmacology, Faculty of Pharmacy, University of Coimbra, 3000-548 Coimbra, Portugal
2Centre for Neuroscience and Cell Biology (CNC), University of Coimbra, 3004-517 Coimbra, Portugal
3Health Sciences Research Centre (CICS), University of Beira Interior (UBI), 6200-506 Covilhã, Portugal
4Department of Internal Medicine, Amato Lusitano Hospital, 6000-085 Castelo Branco, Portugal

Received 14 September 2012; Accepted 10 November 2012

Academic Editor: Ken Yasukawa

Copyright © 2012 Márcio Rodrigues et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

ppCertificate of analysis of Guarana (Paullinia cupana L.) extract 12% caffeine provided by Bio Serae Laboratories (ref. 410044 - batch 0805519).

  1. Supplementary Material