Evidence-Based Complementary and Alternative Medicine / 2012 / Article / Tab 1

Review Article

Role of Mesotherapy in Musculoskeletal Pain: Opinions from the Italian Society of Mesotherapy

Table 1

Tissue levels of Na-ketoprofen (μg) detected by chromatography following local intradermal (LIT) or intramuscular (IM) administration, modified with permission from [23].

Time (hours)SkinMuscleArticular tissue
LITIMLITIMLITIM

0ndndndndndnd
0.5124.94.81.533.325.818.6
142.3t3t19.30.3
215.6t23.8t10.8t
410.9t19.3t8.3t
7tnd100.6t6.2t
10tnd102.2t7t
24ndnd14.9nd0.8nd

nd = not detectable; t = trace.