Research Article

Correlation between Chemical Composition of Curcuma domestica and Curcuma xanthorrhiza and Their Antioxidant Effect on Human Low-Density Lipoprotein Oxidation

Table 3

Percentage inhibition and IC50 value (μg/mL) of the essential oils of Curcuma domestica and C. xanthorrhiza and the essential oil standards on human LDL peroxidation.

SampleConcentration ( g/mL)Inhibition (%)IC50 ( g/mL)

25 78.8 ± 1.2*
12.556.4 ± 1.0
Curcuma domestica 6.2544.8 ± 0.47.8 ± 0.2
3.1327.5 ± 1.5
1.5620.0 ± 0.8

25 86.9 ± 2.3*
12.583.2 ± 1.2
Curcuma xanthorrhiza 6.2564.0 ± 1.32.2 ± 0.1
3.1357.8 ± 4.6
1.5649.4 ± 0.2

12.598.0 ± 0.7*
6.2587.5 ± 2.0
Xanthorrhizol3.1384.5 ± 2.50.4 ± 0.1 (1.9  M)
1.5677.5 ± 0.8
0.7864.6 ± 1.7

12.585.6 ± 0.7*
6.2572.8 ± 1.0
Ar-Turmerone3.1362.2 ± 1.72.2 ± 0.1 (10.2  M)
1.5641.7 ± 1.2
0.7824.6 ± 0.8

25 69.9 ± 0.3*
12.558.1 ± 0.3
Zerumbone6.2555.9 ± 0.75.4 ± 0.4 (24.9  M)
3.1349.0 ± 0.3
1.5627.6 ± 2.9

Geranyl acetate2526 ± 2.6
Zingiberene2516 ± 1.9
Ar-Curcumene254.6 ± 1.2
-Curcumene257.8 ± 1.5
Camphor2511.2 ± 0.4

Values are presented as mean ± SEM ( ). * < 0.05 as compared with the control. IC50 values in M are in parentheses.