Correlation between Chemical Composition of Curcuma domestica and Curcuma xanthorrhiza and Their Antioxidant Effect on Human Low-Density Lipoprotein Oxidation
Table 3
Percentage inhibition and IC50 value (μg/mL) of the essential oils of Curcuma domestica and C. xanthorrhiza and the essential oil standards on human LDL peroxidation.
Sample
Concentration (g/mL)
Inhibition (%)
IC50 (g/mL)
25
78.8 ± 1.2*
12.5
56.4 ± 1.0
Curcuma domestica
6.25
44.8 ± 0.4
7.8 ± 0.2
3.13
27.5 ± 1.5
1.56
20.0 ± 0.8
25
86.9 ± 2.3*
12.5
83.2 ± 1.2
Curcuma xanthorrhiza
6.25
64.0 ± 1.3
2.2 ± 0.1
3.13
57.8 ± 4.6
1.56
49.4 ± 0.2
12.5
98.0 ± 0.7*
6.25
87.5 ± 2.0
Xanthorrhizol
3.13
84.5 ± 2.5
0.4 ± 0.1 (1.9 M)
1.56
77.5 ± 0.8
0.78
64.6 ± 1.7
12.5
85.6 ± 0.7*
6.25
72.8 ± 1.0
Ar-Turmerone
3.13
62.2 ± 1.7
2.2 ± 0.1 (10.2 M)
1.56
41.7 ± 1.2
0.78
24.6 ± 0.8
25
69.9 ± 0.3*
12.5
58.1 ± 0.3
Zerumbone
6.25
55.9 ± 0.7
5.4 ± 0.4 (24.9 M)
3.13
49.0 ± 0.3
1.56
27.6 ± 2.9
Geranyl acetate
25
26 ± 2.6
Zingiberene
25
16 ± 1.9
Ar-Curcumene
25
4.6 ± 1.2
—
-Curcumene
25
7.8 ± 1.5
Camphor
25
11.2 ± 0.4
—
Values are presented as mean ± SEM (). * < 0.05 as compared with the control. IC50 values in M are in parentheses.