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Evidence-Based Complementary and Alternative Medicine
Volume 2012, Article ID 451039, 7 pages
Research Article

Chemical Analysis and Study of Phenolics, Antioxidant Activity, and Antibacterial Effect of the Wood and Bark of Maclura tinctoria (L.) D. Don ex Steud.

1Instituto de Química, Universidade Federal de Uberlândia, Avenida João Naves de Ávila 2121, 38400-902 Uberlândia, MG, Brazil
2Núcleo de Pesquisas em Ciências Exatas e Tecnológicas, Universidade de Franca, Avenida Dr. Armando Salles Oliveira 201, 14404-600 Franca, SP, Brazil

Received 30 September 2011; Accepted 7 December 2011

Academic Editor: Y. Ohta

Copyright © 2012 K. C. Lamounier et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Maclura tinctoria (L.) D. Don ex Steud. has one of the highest qualities among the coefficients for Brazilian woods (up to 9.6) and resistance rates equivalent to Indian teak (Tectona grandis). In this study, the macromolecular constituents and total phenols compounds as well as the antioxidant and antibacterial activities of this wood were evaluated. Total phenols and proanthocyanidin levels were higher in wood when compared with bark levels. The antioxidant activity of wood extracts (IC50 = 18.7 μg/mL) was more effective than that of bark extracts (IC50 = 20.9 μg/mL). Wood and bark extracts revealed a high potential for inhibition of aerobic and anaerobic bacteria. The bark extracts were the most active (MIC from 20 to 60 μg/mL). Both antioxidant activity and high potential for bacteria inhibition turn these extracts promising for drug formulations, especially as antibacterial agent.