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Evidence-Based Complementary and Alternative Medicine
Volume 2012, Article ID 453503, 8 pages
http://dx.doi.org/10.1155/2012/453503
Research Article

Metabonomic Evaluation of ZHENG Differentiation and Treatment by Fuzhenghuayu Tablet in Hepatitis-B-Caused Cirrhosis

1Research Center for Traditional Chinese Medicine and Systems Biology, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Pudong, Shanghai 201203, China
2Institute of Liver Diseases, Shuguang Hospital, Key Laboratory of Liver and Kidney Diseases of Ministry of Education, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
3Research Center for Traditional Chinese Medicine Complexity System, Shanghai University of Traditional Chinese Medicine, 1200 Cailun Road, Pudong, Shanghai 201203, China

Received 13 February 2012; Accepted 28 March 2012

Academic Editor: Shao Li

Copyright © 2012 Shujun Sun et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [24 citations]

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  • Xuan Liu, Wan-Ying Wu, Bao-Hong Jiang, Min Yang, and De-An Guo, “Pharmacological tools for the development of traditional Chinese medicine,” Trends in Pharmacological Sciences, 2013. View at Publisher · View at Google Scholar
  • Jianye Dai, Junwei Fang, Shujun Sun, Qiwen Chen, Huijuan Cao, Ningning Zheng, Yongyu Zhang, and Aiping Lu, “ZHENG-Omics Application in ZHENG Classification and Treatment: Chinese Personalized Medicine,” Evidence-Based Complementary and Alternative Medicine, vol. 2013, pp. 1–9, 2013. View at Publisher · View at Google Scholar
  • Jianye Dai, Shujun Sun, Jinghua Peng, Huijuan Cao, Ningning Zheng, Junwei Fang, Qianhua Li, Jian Jiang, Yongyu Zhang, and Yiyang Hu, “Exploration of Macro-Micro Biomarkers for Dampness-Heat Syndrome Differentiation in Different Diseases,” Evidence-Based Complementary and Alternative Medicine, vol. 2013, pp. 1–9, 2013. View at Publisher · View at Google Scholar
  • Shujun Sun, Jianye Dai, Junwei Fang, Xiaojun Gou, Huijuan Cao, Ningning Zheng, Yang Wang, Wei Zhang, Yongyu Zhang, Wei Jia, and Yiyang Hu, “Differences of Excess and Deficiency Zheng in Patients with Chronic Hepatitis B by Urinary Metabonomics,” Evidence-Based Complementary and Alternative Medicine, vol. 2013, pp. 1–10, 2013. View at Publisher · View at Google Scholar
  • Jianye Dai, Shujun Sun, Jianmei Cao, Yu Zhao, Huijuan Cao, Ningning Zheng, Junwei Fang, Yang Wang, Wei Zhang, Yongyu Zhang, Yiyang Hu, and Zhiwei Cao, “Similar Connotation in Chronic Hepatitis B and Nonalcoholic Fatty Liver Patients with Dampness-Heat Syndrome,” Evidence-Based Complementary and Alternative Medicine, vol. 2013, pp. 1–12, 2013. View at Publisher · View at Google Scholar
  • Junwei Fang, Ningning Zheng, Yang Wang, Huijuan Cao, Shujun Sun, Jianye Dai, Qianhua Li, and Yongyu Zhang, “Understanding Acupuncture Based on ZHENG Classification from System Perspective,” Evidence-Based Complementary and Alternative Medicine, vol. 2013, pp. 1–10, 2013. View at Publisher · View at Google Scholar
  • Ya-Nan Song, Gui-Biao Zhang, Yong-Yu Zhang, and Shi-Bing Su, “Clinical Applications of Omics Technologies on ZHENG Differentiation Research in Traditional Chinese Medicine,” Evidence-Based Complementary and Alternative Medicine, vol. 2013, pp. 1–11, 2013. View at Publisher · View at Google Scholar
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  • Linlin Zhao, Ling Wan, Xinjian Qiu, Ruomeng Li, Shimi Liu, and Dongsheng Wang, “A Metabonomics Profiling Study on Phlegm Syndrome and Blood-Stasis Syndrome in Coronary Heart Disease Patients Using Liquid Chromatography/Quadrupole Time-of-Flight Mass Spectrometry,” Evidence-Based Complementary and Alternative Medicine, vol. 2014, pp. 1–10, 2014. View at Publisher · View at Google Scholar
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  • Ning Jiang, Hong-fang Liu, Si-di Li, Wen-xia Zhou, Yong-xiang Zhang, Qi Zhang, and Xian-zhong Yan, “An integrated metabonomic and proteomic study on Kidney-Yin Deficiency Syndrome patients with diabetes mellitus in China,” Acta Pharmacologica Sinica, 2015. View at Publisher · View at Google Scholar
  • Jian Shi, Bei Cao, Xin-Wen Wang, Ji-Ye Aa, Jin-Ao Duan, Xuan-Xuan Zhu, Guang-Ji Wang, and Chang-Xiao Liu, “Metabolomics and its application to the evaluation of the efficacy and toxicity of traditional Chinese herb medicines,” Journal of Chromatography B, 2015. View at Publisher · View at Google Scholar
  • Qilong Chen, Feizhen Wu, Mei Wang, Shu Dong, Yamin Liu, Yiyu Lu, Yanan Song, Qianmei Zhou, Ping Liu, Yunquan Luo, and Shibing Su, “Transcriptional Profiling and miRNA-Target Network Analysis Identify Potential Biomarkers for Efficacy Evaluation of Fuzheng-Huayu Formula-Treated Hepatitis B Caused Liver Cirrhosis,” International Journal of Molecular Sciences, vol. 17, no. 6, pp. 883, 2016. View at Publisher · View at Google Scholar
  • Xu Tong, Qingyu Xie, Guang Rong, Sheng Zhou, and Qinggang Meng, “Detection of consensuses and treatment principles of diabetic nephropathy in traditional Chinese medicine: A new approach,” Journal of Traditional Chinese Medical Sciences, 2016. View at Publisher · View at Google Scholar
  • Tao Wang, Xuelin Zhou, Honghong Liu, Jiabo Wang, Ping Zhang, Yun Zhu, Kun Li, Shizhang Wei, Haotian Li, Lifu Wang, Ruilin Wang, and Yanling Zhao, “Fuzheng Huayu capsule as an adjuvant treatment for HBV-related cirrhosis: A systematic review and meta-analysis,” Phytotherapy Research, 2017. View at Publisher · View at Google Scholar
  • Shu Dong, Fei-fei Cai, Qi-long Chen, Ya-nan Song, Yang Sun, Bin Wei, Xiao-yan Li, Yi-yang Hu, Ping Liu, and Shi-bing Su, “Chinese herbal formula Fuzheng Huayu alleviates CCl4-induced liver fibrosis in rats: a transcriptomic and proteomic analysis,” Acta Pharmacologica Sinica, 2017. View at Publisher · View at Google Scholar
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  • Qing Ji, Yunquan Luo, Feifei Cai, Shibing Su, Wenhai Wang, Yiyu Lu, Wanli Deng, and Qi Li, “Characteristic proteins in the plasma of postoperative colorectal and liver cancer patients with Yin deficiency of liver-kidney syndrome,” Oncotarget, vol. 8, no. 61, pp. 103223–103235, 2017. View at Publisher · View at Google Scholar
  • Xue-Qing Hu, Bin Wei, Ya-Nan Song, Qing Ji, Qi Li, Yun-Quan Luo, Wen-Hai Wang, and Shi-Bing Su, “Plasma metabolic profiling on postoperative colorectal cancer patients with different traditional Chinese medicine syndromes,” Complementary Therapies in Medicine, vol. 36, pp. 14–19, 2018. View at Publisher · View at Google Scholar
  • Chao-qun Zhao, Long Chen, Hong Cai, Wei-li Yao, Qun Zhou, Hui-ming Zhu, Yue Gao, Ping Liu, Xiao-jun Gou, and Hua Zhang, “Classification of Gan Dan Shi Re Pattern and Gan Shen Yin Xu Pattern in Patients with Hepatitis B Cirrhosis Using Metabonomics,” Evidence-Based Complementary and Alternative Medicine, vol. 2018, pp. 1–13, 2018. View at Publisher · View at Google Scholar
  • Xue-Qing Hu, Ya-Nan Song, Rong Wu, Fei-Fei Cai, Yongyu Zhang, Yi-Yang Hu, and Shi-Bing Su, “Metabolic mechanisms of Fuzheng-Huayu formula against liver fibrosis in rats,” Journal of Ethnopharmacology, pp. 111888, 2019. View at Publisher · View at Google Scholar
  • Zefang Dang, Qiagnhua Li, Shujun Sun, Yang Wang, Rui Lin, Yongyu Zhang, Jianye Dai, and Ningning Zheng, “The Medicinal Plant Pair Bupleurum chinense-Scutellaria baicalensis – Metabolomics and Metallomics Analysis in a Model for Alcoholic Liver Injury,” Frontiers in Pharmacology, vol. 10, 2019. View at Publisher · View at Google Scholar