Impact of Global Normalization in fMRI Acupuncture Studies

Table 5

Nonspecific and specific BOLD responses evoked by acupuncture stimulation.

			Acupuncture					Acupuncture > tactile
Regions			Talairach		𝑡-value	Voxels		Talairach		𝑡-value	Voxels
		x	y	z			x	y	z
Brainstem
Midbrain	L	−15	−23	−1	5.57	5
	R	9	−15	−2	5.97	7
Inferior frontal gyrus
B A47	R	42	20	−14	7.2	5
Precentral gyrus
BA 6, 44	L	−48	−3	6	6.4	9
	R	56	−3	6	6.3	5	33	−9	56	3.91	6
Cingulate gyrus
BA 24	L	−9	13	32	6.6	9
Postcentral gyrus
BA 2, 3	L	−18	−35	65	7.91	19
	R	65	−22	31	6.05	5
BA 40	L	−53	−28	21	7.46	20
Inferior parietal lobule
BA 40	L	−65	−31	29	8.14	51
	R	59	−42	38	7.13	36
Thalamus	L	9	−17	1	6.68	27
	R	−15	−20	7	6.4	44
Insula
BA 13	L	−50	−31	18	7.21	32
Claustrum
	L	−36	0	3	6.09	8
Superior parietal lobule
BA 7	L						−12	−61	56	4.11	3
	R						21	−50	58	3.73	12
Precuneus
BA 7, 19	L						−9	−58	58	3.97	11
	R						18	−56	53	3.77	8
Superior temporal gyrus
BA 22, 38, 41, 42	L	−59	−34	21	6.57	38
	R	59	9	−3	6.51	7
Cerebellum
Dentate	L	−15	−62	−25	8.19	11
Declive	L	−18	−65	−22	7.37	28
Pyramis	L	−15	−65	−27	6.81	5
Uvula	L	−18	−68	−24	6.48	5

The coordination of voxel with the maximal 𝑡 within each region is listed. The regions are thresholded at 𝑃<0.00001, uncorrected for “acupuncture” and at 𝑃<0.001, uncorrected for “acupuncture > tactile.”
Abbreviations: BA: Brodmann area; L: left; R: right.