A Study of the Wound Healing Mechanism of a Traditional Chinese Medicine, Angelica sinensis, Using a Proteomic Approach

Figure 1

Effects of AS extract or FA on cell viability after 24 hr treatment in human fibroblast. Graph represents the ratio of cell viability compared with the DMSO control. (a) AS extract promotes cell growth in a dose dependent manner up to 400 μg/mL, but FA treatment (b) has no significant effect on cell proliferation. Fibroblasts were seeded in a 24 well plate with 4 × 10⁴ cells per well. After the cells were attached, different drug concentrations were added for 24 hr and cell proliferation was evaluated by WST-1 assay at OD₄₅₀−OD₆₉₀. The control was treated with 0.1% DMSO only. The Student’s 𝑡 test was used to evaluate the statistical significance of the results, which are presented as mean ±SD (𝑛=5). *𝑃<0.05, **𝑃<0.01, compared with the control.

(a)

(b)